I don't know. I love what Ciggy has done with that offensive set and it forces the LB's to think and be very disciplined, but if i'm playing the role of the armchair DC i'd just put 8 men in the box in some sort of zone and let my corners go man to man vs our receivers who can't seem to get open on their own.
This offense needs a vertical threat that commands attention from a safety on just about every play. As it stands now i think DC's will adjust to the Gurley/Tavon behind the LOS show.