I think this falls into 2 distinct pieces.
1) If the starting D line is in, I think the game is much less close and we win in a very convincing but still somewhat sad fashion to the tune of 19-10
2) The game was tied before the pick 6. I blame Cooper, Keenum, and Boras equally. Those points started the loss. That was the point from which we didn't recover.
Fisher had opportunities to get the game back, and blew it, but we were already down. At that point your hoping someone can do something to get a win back. The loss is already on the table by the time Fisher is trying to manufacture a win and overcome the pick 6. It feels different to me anyway.